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At SCOPE we specialize in pain management clinical trials — from mild and acute to severe, chronic, and breakthrough pain. Our expert team designs tailored strategies for drugs, devices, or combination products, managing every phase from concept to delivery.
SCOPE has conducted over 55 pain studies at more than 1,700 clinical sites, involving 12,000 patients across adult and pediatric indications. Our extensive network —comprising neurologists, pain clinics, palliative specialists, surgeons, anesthesiologists, general practitioners, and key opinion leaders — ensures rapid, accurate feasibility assessments and trial success.
Your program is overseen by experienced clinical research associates, project managers, and medical monitors who understand the nuances of pain studies. As pain is subjective, choosing the right instrument to measure the primary endpoint is crucial. Our experts advise on appropriate, guideline-compliant tools, including:
Primary pain endpoints must directly capture a patient’s pain intensity, as per FDA guidelines. Yet, paper diaries often burden patients, especially when in pain, impacting compliance and data quality.
At SCOPE, we minimize this burden by using electronic clinical outcome assessments (eCOA) such as ePRO and eDiary, enabling data capture via apps or web on tablets, smartphones, or PCs.
At SCOPE, we partner with select providers for electronic Clinical Outcome Assessments (eCOA). Our monitors train patients on self-rated pain scales and ensure timely data capture, while ongoing site communication maintains quality and consistency.
Our project managers identify and mitigate study risks early. For trial participants unable to self-report — such as young children — observers (e.g., parents, caregivers) provide Observer-Reported Outcomes (ObsRO) based on observable signs like wincing, crying, or squirming. Clinician-reported outcomes are similarly limited to observable data.
SCOPE has extensive experience in the requirements for handling of controlled drugs / narcotics with a network of local offices capable of ensuring compliance with local regulation and avoiding issues with handling.
e.g. Arthritis-related Pain, Bladder Pain Syndrome, Cancer Pain, Chronic Pain, Headache / Migraine, Lower Back Pain, Neuropathic Pain (diabetic, postherpetic), Postoperative Pain Management, Rheumatic Pain, Acute Postoperative / Procedural Pain
e.g. ART (IVF, ICSI), Contraception, Endometriosis, Fibromyalgia Syndrome (FMS), Obstetrics, Oncology, Pain Management, PCOS, Polymyalgia Rheumatica, Postmenopausal Complaints, Preterm labor, Rheumatoid Arthritis, Vaginitis, Vulvar and Vaginal Atrophy, Vulvovaginal Candidiasis
e.g. Asthma (mild, moderate, severe, paediatric), Asthma / COPD Overlap Syndrome (ACOS), Chronic Obstructive Pulmonary Disease (COPD), Community-Acquired Pneumonia (CAP), Respiratory VirusInfection (including paediatric)
e.g. Alzheimer’s Disease, Bipolar Disorder, Depression, Epilepsy (including paediatric), Mania, Multiple Sclerosis, Narcolepsy, Parkinson’s Disease, Sensorineural Disorder
e.g. Community-acquired pneumonia (CAP), COVID-19, GI and Intra-Abdominal Infections, Immune-Modulator to prevent SARS-CoV Complication, Respiratory Virus Infections (including paediatric)
e.g. Cell and Gene Therapies, Early-Phase Clinical Development of ATMPs, Immunotherapy, Personalized Therapies, Regenerative Medicine
We support projects focusing on conditions such as hypertension, myocardial infarction, and pulmonary arterial hypertension – all high-impact topics in cardiovascular care and research.
Our experience spans across immune-related areas like allergies and vaccinations – key therapeutic fields with growing relevance.
We help communicate complex topics in metabolic disorders, including type 1 diabetes, where patient education and clarity are crucial.
From Non-Hodgkin lymphoma to various solid tumors – such as bladder, breast, colorectal, or prostate cancer – we bring clarity to oncology and hematology communication.
We develop content for dental indications such as periodontitis, caries prevention, oral mucositis, and temporomandibular disorders – always with precision and sensitivity.
We work on indications like alopecia areata, hypertrophic scars, and psoriasis – conditions that often impact both physical and emotional wellbeing.
Our projects cover topics such as diabetes, hormonal imbalances, and metabolic disorders – essential areas in endocrinology.
From Crohn’s disease and ulcerative colitis to irritable bowel syndrome and reflux – we translate complex GI conditions into clear communication.
We support education and awareness campaigns on hepatitis B and C, liver fibrosis, non-alcoholic fatty liver disease (NAFLD), and cirrhosis – all major topics in liver health.
Conditions like rheumatoid arthritis and polymyalgia rheumatica require nuanced and evidence-based communication – a strength we bring to every campaign.
Whether it’s conjunctivitis or retinopathy – we create accessible content for eye disorders aimed at both professionals and patients.
Rare diseases like idiopathic sudden sensorineural hearing loss demand tailored, precise messaging – we’re here to deliver just that.
We support communication around orthopedic topics such as cartilage defects and osteoarthritis – with a focus on clarity and empathy.
From sudden hearing loss and rhinitis to rare conditions like Schwannomas – we bring ENT topics to life with targeted messaging.
We cover a range of urological topics – from bladder and prostate cancer to bladder pain syndrome and kidney cancer – always with scientific accuracy and approachability.
Our work includes vaccine communication for Hepatitis B, influenza, rabies, and tuberculosis – complex topics made clear and compliant.
